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47 pairs have negative mean SSIM: the source and target are anti-correlated, sharing less structure than random noise. The worst offenders:
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Agar was first introduced into the laboratory in 1881. Since then, microbiologists have depended on agar to create strong jellies. When microorganisms are streaked or plated onto this jellied surface and incubated, individual cells multiply into distinct colonies that scientists can easily observe, select, and propagate for further experiments. Many of the most important findings in biological research of the last 150 years or so — including the discovery of the CRISPR/Cas9 gene-editing tool — have been enabled by agar.4 Agarose, a derivative of agar, is also essential in molecular biology techniques like gel electrophoresis, where its porous gel matrix separates DNA fragments by size, enabling researchers to analyze and isolate specific genetic sequences.
Michael has since apologized for both incidents, took a brief detour as a SPAC CEO, yet found himself back in Washington when Donald Trump tapped him in December 2024 to become undersecretary of defense for research and engineering—effectively the Pentagon’s chief technology officer. The Senate confirmed him in 2025, installing a Silicon Valley–trained business executive at the center of how the War Department thinks about AI, autonomy, and advanced weapons systems.